Monday, January 27, 2020

Blood pressure and heart rate in humans

Blood pressure and heart rate in humans Introduction: Blood pressure is the measurement of arterial pressure as a result of the contraction and relaxation of the heart. The pressure upon the contraction of the heart is normally defined as the systolic pressure while the pressure upon relaxation is referred to as the diastolic pressure. Both are measured in milliliters of mercury (mm Hg) and are most important in measuring a healthy blood pressure. The heart rate, which is usually expressed in beats per minute, is also important when measuring the strength and wellness of a heart. An individual with a healthy heart will usually have a systolic pressure of 120 mmHg and a diastolic pressure of 80 mmHg (Bishop 2009). A normal heart rate is within the range of 60 bpm and 80 bpm (Weedman 2009). The most common way to measure an individuals blood pressure and heart rate is with a sphygmomanometer, a machine that when used correctly is able to accurately determine a persons blood pressure. Both blood pressure and heart rate are unfixed and constantly changing in response to the body. Factors such as diet, exercise and physical and psychological stress can alter the arterial pressure. An individuals blood pressure will increase when the vessels in the body constrict while the heart tries to continually pump the same amount of blood throughout the body. The blood pressure will decrease when the vessels increase in diameter and blood is able to flow through them with ease. High blood pressure is referred to as hypertension while low blood pressure is referred to as hypotension. An individuals body might react to pain or stress with an increase in blood pressure or respond to constant and frequent exercise with an over all decrease in blood pressure over a period of time. Hydration is an important part of the circulatory system. Appropriate hydration is crucial for normal body function. Hydration helps to distribute the necessary nutrients, regulate body temperature and dispose of waste within the body (Patterson, 2005). Water should make up approximately 60% of an adults body weight. A lack of proper hydration can affect blood volume, plasma volume and the volume of red blood cells in the body (Costill 1974). In the experiment we designed and performed in class, we wanted to observe different factors affecting blood pressure. We asked the question, â€Å"Does hydration effect an individuals blood pressure and heart rate?† We then generated a testable hypothesis that the consumption of water will increase blood pressure as well as heart rate. Materials and Methods: We began the experiment by choosing two variables, dependant and independent. The independent variable was ingestion of 16 ounces of water in order to hydrate an individual; the dependant variable was the measured heart rate and blood pressure. We also designated our experimental replicates groups. All together there were a total of 26 individuals in the experimental group. The entire experimental group was divided into pairs. When blood pressure and heart rate were taken throughout the experiment, they were taken by the individuals partner. We took three basal / resting blood pressure readings. To do so we placed the blood pressure cuff on the left arm of the individual tested and used the sphygmomanometer to determine the individuals resting systolic and diastolic blood pressure as well as his/her heart rate. To correctly situate the pressure cuff on the arm, we assured that the cuff was placed approximately 3 cm above the elbow. We made sure there was no bulky clothing between th e individuals arm and the cuff. The tube leading from the sphygmomanometer to the cuff was situated on the innermost side of the arm, near the brachial artery (Weedman 2009). When wrapping the pressure cuff around the arm, we assured that it was neither too snug or to loose. We pumped the cuff with the rubber bulb until it reached 150 mm Hg. To do so required that we squeeze the bulb while our finger covered the air hole and releasing to allow the bulb to refill. Once at 150mm Hg, the sphygmomanometer gradually released the pressure until the digital reading came up on the screen. We then recorded the data and repeated this step two more times to have a total of three basal readings. After retrieving the resting blood pressure, we had the individual consume about two cups (16 oz) of water quickly (less than one minute) and the partner immediately took a blood pressure reading with the sphygmomanometer. We followed the initial post reading with four more readings in time intervals of three minutes switching off between partners. We recorded the systolic, diastolic, and heart rate for each of these readings. The cuff was taken off after each reading to allow the pressure to be reestablished in the individual between each reading. Throughout the experiment, the data was collected by each individual and then collected and put into an excel spreadsheet. The data that was collected included each subjects basal and experimental blood pressure and heart rate readings along with the relative temperature of the water consumed (cold or room temperature). The collected data was then analyzed using different forms of statistics. We used a â€Å"T test† as well as dividing relevant data into subgroups and found the range and average of the data. Results: In this experiment, we exposed a group of 26 individuals to dehydration and then had them consume a total of 16 ounces to rehydrate. Their blood pressure was then taken immediately as well as in intervals of three minutes for a total of twelve minutes. We predicted that hydrating an individual would increase their blood pressure and decrease the heart rate, however, we found that hydration in fact does the opposite. When organizing and reviewing the data for this experiment it is clear that our results for this experiment were relevant. Our data was calculated based on averages of pulse rates and blood pressures. Our averaged data was then organized in graphs and tables that were divided into subgroups based on the temperature of the water consumed (cold, room temperature, and unknown temperature). Finally, the ranges of each subgroup and T-tests were calculated based off of our data. We calculated three T-tests from our data. One T-test used results of average pulse rate readings from the cold, room temperature, and unknown water consumed. Another T-test was calculated from the average systolic results from the cold water, room temperature water, and the unknown water consumed. The final T-test used the average diastolic results from the cold water, room temperature water, and unknown water consumed. The values for each T-test can be seen in Tables 1, 2, and 3, T-tests. Because the values for each of the T-test was less than 5%, it can be concluded that the data collected shows a correlation between hydration and blood pressure and heart rate. In graph 1, the room temperature graph, the heart rate overall decreased. In graph #2, the second room temperature graph, the systolic and diastolic pressures also decreased. In the cold water heart rate graph, graph #3, the heart rate drastically increased. In graph #4, both the systolic and diastolic pressures decreased. Finally, in graph #3, the graph showing unknown temperatures of the water, the heart rate had an overall decrease. Graph #4 showed that the diastolic pressure had an overall decrease in pressure while the systolic had an overall slight increase. Discussion: Originally, we hypothesized that blood pressure and heart rate would be affected by hydration. We predicted that an increase in hydration would proportionally increase the blood pressure and heart rate. Our results do to some extent support our hypothesis and predictions. Our results show that hydration does affect blood pressure and heart rate. Our data collected generally shows that hydration, over a short period of time, will overall decrease the arterial pressures (systolic and diastolic) as seen in Graphs 2, 4, and 6. The data in each subgroup also shows that pulse rate will be affected differently by different temperatures of water. When ingesting cold water, the pulse rate generally increases, while those that consumed room temperature water have a decreased pulse rate as seen in Graph 1 and 3. A hypothesis that would correctly support the results of this experiment would be, â€Å"Hydration (the consumption of water) will decrease blood pressure while cold water will increase heart rate.† Though this hypothesis is accurately supported by the results, this hypothesis may also be incorrect. One way it can be determined that our results wholly support our hypothesis is the value of the T-tests calculated for this experiment. The value of the T-tests based off of the average pulse rate, systolic pressure, and diastolic pressure were all below 5%. This shows low variability within the experiment and suggests that our experimental results are valid. Because the T-test was below 5%, it can be concluded that our results from this experiment are significant. Our results support the fact that hydration does decrease blood pressure. After much research, it is shown that, â€Å"dehydration and blood pressure are linked that it is not aging that leads to High Blood Pressure, but rather dehydration.† (Healthy Water 2007). Our results for our experiment relate to this statement because our data shows that hydration lowers blood pressure, and inversely suggests that dehydration would do the opposite by increasing blood pressure. When an individual is dehydrated, their blood vessels compensate the lack of water by contracting and heightening blood pressure. When an individual is sufficiently hydrated their vessels are filled with a high blood volume that holds the vessels open and relaxed while transporting water to fundamental organs and systems throughout the body. There were many weaknesses and flaws in our experiment and experimental design. One flaw in experimental design was the lack of a control group. Though basal readings were taken prior to the experiment, there was no separate group that was not treated with the independent variable and measured throughout the experiment. Also, our experiment was done in a hurry that could have affected the blood pressure and heart rate throughout the experiment. The sphygmomanometers that were used often came up with â€Å"error† which may have contributed to the insignificance of our data. Finally, there was no way of measuring the level of dehydration of the experimental group prior to drinking the 16 ounces of water. The data will vary with the different levels of hydration and without knowing the exact level of hydration of each individual it would be impossible to group them together. Though our results did not match our hypothesis, they were comparable to similar experiments. Our data did show that an increase in hydration will decrease blood pressure. However, our data and experimental design is neither accurate or acceptable due to errors in experimental design and experimental flaws. Literature Cited: Bishop T. 2009.Measuring Blood Pressure. Practice Nurse 38: 11-16. Costill DL, Dill DB. 1974. Calculation of percentage changes in volumes of blood, plasma, and red cells in dehydration. Journal of Applied Physiology 37: 247-248. Healthy Water. 2007. Dehydration and Blood Pressure disorders are linked. http://www.healthy-water-best-filters.com/dehydration-blood-pressure.html. February 20, 2009. Patterson SM, Rochette LM. 2005. Hydration status and cardiovascular function: effects of hydration enhancement on cardiovascular function at rest and during psychological stress. International Journal of Psychophysiology 56: 81-91. Weedman D, Sokoloski ES. 2009. Biology of Organisms. 5th Edition. Mason, OH: Cengage Learning. P 173-184.

Sunday, January 19, 2020

Comparing the Hero in Beowulf and Sir Gawain and the Green Knight Essay

Beowulf and Sir Gawain – True Heroes Heroes come in many forms. The construction of "the heroic" has taken many forms, yet traits such as: courage, honor, and loyalty, reappear as themes throughout the "hero" personality. The characters of Beowulf and Sir Gawain each represent a version of a hero, yet each comes across quite differently in their story. A hero can be said to truly win if he remains constant to his noble values when put in any situation that crosses his way. When measured by that criterion, Sir Gawain stands out above Beowulf as a true hero, due to his command of both personal and spiritual power through the use of thought, as well as valiant deeds. The character of Beowulf stands as a hero to the ancient Danes because of his actions. He is constantly being cited as a "war-chief" and a "gold-giver" (61). Beowulf has achieved fame through what he has done with his own hands. His identity as a leader is based upon the Danish society’s emphasis on personal action, as opposed to the delegation of responsibility through conscious thought. It is this very sense which spurs Beowulf to fight the dragon: "In my youth I engaged in many wars. Old guardian of the people, I shall still seek battle, perform a deed of fame, if the evil-doer will come to me..." (59). Beowulf derives his power from a strong link to the past. Without his history of glorious deeds, he would see himself bereft of the very power which qualifies him to be a good King. Beowulf’s bravery never comes in to question, he does meet every challenge head-on, with deadly attention. The society which labels Beowulf as a legendary hero, recognizes his actions and his bravery as a integral part of his definition as a hero. Without the society to support th... ...or a chivalric Knight embodies the battle of the righteous self against corruption. Gawain’s strength comes from his discovery of his own flaws. Beowulf’s ideals concerning honor and nobility exist only within the context of his society. Remove him from other people, and his life would be meaningless. This is the true flaw of Beowulf, which the character of Gawain, by the end of his story, comes to realize. The notion of "winning" can be applied at all times to the personality of the chivalric Knight. The battleground becomes the mind, which is separate from the realm of reality. Beowulf does not have the capability to win, without the recognition of his fellow warriors. Within the mind, all sorts of battles are waged. The true winner is the person who can learn from that struggle, and who is able to apply that knowledge within both solitary and societal venues. Â  

Saturday, January 11, 2020

KES- the film /movie

â€Å"While A Kestrel for a Knave begins with a sense of hope, it soon becomes clear that the novel and film are both ultimately about Billy's defeat. † Is one that I agree with. It's explores the theme of hope In both a positive and negative manner. The audience learns that hope can be nurtured through the support of adults and also when an individual has a goal they wish to attain.Yet, it's abolished when a teenager is succumbed to despair due to not being rendered with support, and shows the harsh reality for many teenagers dwelling in poverty whereby they experience the absence of hope. I believe this book resonates with teenagers in a contemporary society, as adults can hinder or encourage teenagers dealing with adversely such as bullying, poverty, or family abuse. Also, It suggests that due to the perils of life, teenagers may be deprived of hope when they realist that regardless of their goals and determination, they may never succeed.As evident in the murder of the Kes trel which was Bilge's only source of hope despite adversities. The statement â€Å"While A Kestrel for a Knave begins with a sense of hope, it soon becomes clear that he novel and film are both ultimately about Billy's defeat. † is one that I agree with. It's explores the theme of hope In both a positive and negative manner. The audience learns that hope can be nurtured through the support of adults and also when an individual has a goal they wish to attain.Yet, it's abolished when a teenager is succumbed to despair due to not being rendered with support, and shows the harsh reality for many teenagers dwelling in poverty whereby they experience the absence of hope. I believe this book resonates with teenagers in a contemporary society, as adults can hinder or encourage teenagers dealing with adversities such as bullying, poverty, or family abuse. Also, It suggests that due to the perils of life, teenagers may be deprived of hope when they realist that regardless of their goa ls and determination, they may never succeed.As evident in the murder of the Kestrel which was Bilge's only source of hope despite adversities. The statement â€Å"While A Kestrel for a Knave begins with a sense of hope, it soon becomes clear that the novel and film are both ultimately about Billy's defeat. † is one that I agree with. It's explores he theme of hope in both a positive and negative manner. The audience learns that hope can be nurtured through the support of adults and also when an Individual has a goal they wish to attain.Yet, it's abolished when a teenager is succumbed to despair due to not being rendered with support, and shows the harsh reality for many teenagers dwelling in poverty whereby they experience the absence of hope. I believe this book resonates with teenagers in a contemporary society, as adults can hinder or encourage teenagers dealing with adversities such as bullying, poverty, or Emily abuse. Also, it suggests that due to the perils of life, t eenagers may be deprived of hope when they realist that regardless of their goals and determination, they may never succeed.As evident in the murder of the Kestrel which was Bilge's only source of hope despite adversities. The statement â€Å"While A Kestrel for a Knave begins with a sense of hope, it soon becomes clear that the novel and film are both ultimately about Billy's defeat. † is one that I agree with. It's explores the theme of hope in both a positive and negative manner. The audience learns that hope can be sis to attain. Yet, it's abolished when a teenager is succumbed to despair due to not being rendered with support, and shows the harsh reality for many teenagers dwelling in poverty whereby they experience the absence of hope.I believe this book resonates with teenagers in a contemporary society, as adults can hinder or encourage teenagers dealing with adversities such as bullying, poverty, or family abuse. Also, it suggests that due to the perils of life, teen agers may be deprived of hope when they realist that regardless of their goals and determination, they may ever succeed. As evident in the murder of the Kestrel which was Bilge's only source of hope despite adversities.The statement â€Å"While A Kestrel for a Knave begins with a sense of hope, it soon becomes clear that the novel and film are both ultimately about Billy's defeat. † is one that I agree with. It's explores the theme of hope in both a positive and negative manner. The audience learns that hope can be nurtured through the support of adults and also when an individual has a goal they wish to attain. Yet, it's abolished when a teenager is succumbed to despair due to not being endured with support, and shows the harsh reality for many teenagers dwelling in poverty whereby they experience the absence of hope.I believe this book resonates with teenagers in a contemporary society, as adults can hinder or encourage teenagers dealing with adversities such as bullying, p overty, or family abuse. Also, it suggests that due to the perils of life, teenagers may be deprived of hope when they realist that regardless of their goals and determination, they may never succeed. As evident in the murder of the Kestrel which was Bilge's only source of hope despite adversities.

Friday, January 3, 2020

Eli Lilly and Company Case Analysis Essay - 1599 Words

Eli Lilly and Company Case Analysis The case under analysis, Eli Lilly Company, will be covering the positives and negatives with regards to the business situation and strategy of Eli Lilly. One of the major pharmaceutical and health care companies in its industry, Lilly focused its efforts on the areas of drug research, development, and marketed to the following areas: neuroscience, endocrinology, oncology, cardiovascular disease, and womens health. Having made a strong comeback in the 1990s due to its remarkably successful antidepressant Prozac, was now facing a potential loss in profits with its patent soon to expire. The problem was not only the soon to expire patent on Prozac, but the fact that Prozac accounted for as much†¦show more content†¦Additional issues that seem to have hampered performance were their failure to meet international sales expectations, expiration of key patents, and its poor performance against competitors. On some measures this can be attributed to the fact that Lillys rigid, cen trally controlled operating structure did not fit well with todays rapidly changing pharmaceutical market environment. Although a culture change may be evident to boost company performance, the leadership would without out a dought face resistance in any effort to lead organizational change at Lilly, especially change of organizational culture. (Greenberg, Jerald p 132-133) External global conditions The firms external environment consists of three main sectors: the Remote Environment, the Industry Environment, and the Operating Environment. All of these environmental sectors affect the firms operations both on an international and domestic level. In comparing these conditions with Eli Lilly its no wonder they were scrambling for an effective strategy that would keep them at the top of there game. The Remote sector is comprised of five factors that are not influenced by a single firm. The main factors are: economic, social, political, technological, and ecological. The managed health care programs launched by the ClintonShow MoreRelatedCase Analysis : Corporate Venture Capital Of Eli Lilly And Company2553 Words   |  11 PagesIntroduction Colonel Lilly founded Eli Lily and Company in 1876, because he felt there was a lack of high quality medicine on the market at the time. He also felt the most medicines on the market were ineffective in the curing of ills. In the case â€Å"Review Corporate Venture Capital at Eli Lilly and Company†, describes the issues surrounding Eli Lily and Company venture capital arm by showing the struggles the company went through in establishing a corporate venture capital fund. It takes you throughRead MoreEli Lilly and Company Analysis946 Words   |  4 PagesEli Lilly and Company Analysis Overview of Eli Lilly: Eli Lilly and Company is a pharmaceutical company that integrates many departments and supply-chain management. The company in itself discovers, develops, manufactures, and sells its drug. The company’s smaller segment also includes animal health business. They manufactures and distribute its products through either leased or owned facilities throughout the United States, Puerto Rico, and several other countries (25), selling in approximatelyRead MoreEli Lilly Ranbaxy joint venture Essay1488 Words   |  6 PagesSummary The Eli Lilly Ranbaxy joint venture allowed both Eli Lilly and Ranbaxy as separate companies to grow and expand as one venture. The support and reliability that both companies had with one another allowed for a strong business relationship to form which led to the same business strategy vision and goals. This joint venture eliminated trade with other companies for the same thing that one another could share to become one of the largest and most successful pharmaceutical companies in the IndianRead MoreJoint Venture Agreements1108 Words   |  5 PagesEli Lilly in India Case Study BUS 545 – Global Business Management May 31, 2015 Andrew Juarez Professor Barnett â€Æ' Executive Summary This report provides an analysis and evaluation of the case study â€Å"Eli Lilly in India†. The general overview of the case study is the discussion of the Joint Venture agreements between two parties. Eli Lilly a reputable pharmaceutical company entered the Indian market in a joint venture agreement with Ranbaxy. The joint venture between both parties was initiallyRead MoreCase Study: Health Care Industry (Eli Lilly and Company)1735 Words   |  7 PagesCASE STUDY: HEALTH CARE INDUSTRY (ELI LILLY AND COMPANY) Introduction: Following on his experience of medicines used in the Civil War, Colonel Eli Lilly, a Union Officer and a pharmacist, started a small pharmaceutical company in Indianapolis, Indiana, USA with the aim of producing high quality prescription drugs. After Colonel Lillys death, his son Josiah K. Lilly Sr., and eventually his two grandsons, Eli Lilly and Josiah K. Lilly Jr., each served as president of the company. It was his grandsonRead MoreEli Lilly in India3134 Words   |  13 PagesEli Lilly in India: Rethinking the Joint Venture Strategy Case Study Analysis – Final Exam Submitted by Lloyd Stallings April 15, 2012 IMAN 615: Dr. Daniel E. Gilbert Eli Lilly in India: Rethinking the Joint Venture Strategy Executive Summary Eli Lilly and Company is a pharmaceutical company, founded in 1876, that integrates many departments and supply-chain management.    The company in itself discovers, develops, manufacturesRead MoreEli Lilly Case3871 Words   |  16 PagesCompeting through Strategy Case: Eli Lilly in India: Rethinking the Joint Ventures Strategy I. Brief Summary Global pharmaceuticals had presence in India since early 80’s and it was not until 1993 that Eli Lilly International decided to establish a Joint Venture with India’s second largest laboratory and exporter, Ranbaxy. This move happened in a very challenging context as both companies have very different profiles and backgrounds. The main differential characteristic was the nature of theirRead MoreEli Lilly: the Evista Project1575 Words   |  7 PagesC580 – Operations Management Eli Lilly: The Evista Project Case Study - Krishna Tavvala Background: Eli Lilly is a leading pharmaceutical company specializing in treatment of diseases like the depression, schizophrenia, diabetes, infections, osteoporosis among others. Evista, a newly developed drug by Eli Lilly, is an estrogen replacement therapy medicine for prevention of post-menopausal osteoporosis which also appeared to lower the incidence of breast cancer in women. This FDA approved drugRead MoreEli Lilly Case3863 Words   |  16 PagesCompeting through Strategy Case: Eli Lilly in India: Rethinking the Joint Ventures Strategy I. Brief Summary Global pharmaceuticals had presence in India since early 80’s and it was not until 1993 that Eli Lilly International decided to establish a Joint Venture with India’s second largest laboratory and exporter, Ranbaxy. This move happened in a very challenging context as both companies have very different profiles and backgrounds. The main differential characteristic was the natureRead MoreEli Lilly: the Evista Project1583 Words   |  7 PagesC580 – Operations Management Eli Lilly: The Evista Project Case Study - Krishna Tavvala Background: Eli Lilly is a leading pharmaceutical company specializing in treatment of diseases like the depression, schizophrenia, diabetes, infections, osteoporosis among others. Evista, a newly developed drug by Eli Lilly, is an estrogen replacement therapy medicine for prevention of post-menopausal osteoporosis which also appeared to lower the incidence of breast cancer in women. This FDA approved drug is